Reproductive BioMedicine Online
Volume 20, Issue 3 , Pages 324-327 , March 2010

Progressive alcohol-induced sperm alterations leading to spermatogenic arrest, which was reversed after alcohol withdrawal

  • Nathalie Sermondade

      Affiliations

    • Service d’Histologie et Biologie de la Reproduction, Assistance Publique Hôpitaux de Paris (APHP)–Hôpital Tenon, Paris, France
    • ER9, Université Pierre et Marie Curie (Paris VI), Paris, France
    • Service d’Histologie-Embryologie-Cytogénétique-Biologie de la Reproduction-CECOS, APHP–Hôpital Jean Verdier, Bondy, France
    • Corresponding Author InformationCorresponding author.
    • ,
  • Hanène Elloumi

      Affiliations

    • Service d’Histologie et Biologie de la Reproduction, Assistance Publique Hôpitaux de Paris (APHP)–Hôpital Tenon, Paris, France
    • ER9, Université Pierre et Marie Curie (Paris VI), Paris, France
    • ,
  • Isabelle Berthaut

      Affiliations

    • Service d’Histologie et Biologie de la Reproduction, Assistance Publique Hôpitaux de Paris (APHP)–Hôpital Tenon, Paris, France
    • ER9, Université Pierre et Marie Curie (Paris VI), Paris, France
    • ,
  • Emmanuelle Mathieu

      Affiliations

    • Service de Gynécologie-Obstétrique et Médecine de la Reproduction, APHP–Hôpital Tenon, Paris, France
    • ,
  • Vanina Delarouzière

      Affiliations

    • Service d’Histologie et Biologie de la Reproduction, Assistance Publique Hôpitaux de Paris (APHP)–Hôpital Tenon, Paris, France
    • ER9, Université Pierre et Marie Curie (Paris VI), Paris, France
    • ,
  • Célia Ravel

      Affiliations

    • Service d’Histologie et Biologie de la Reproduction, Assistance Publique Hôpitaux de Paris (APHP)–Hôpital Tenon, Paris, France
    • ER9, Université Pierre et Marie Curie (Paris VI), Paris, France
    • ,
  • Jacqueline Mandelbaum

      Affiliations

    • Service d’Histologie et Biologie de la Reproduction, Assistance Publique Hôpitaux de Paris (APHP)–Hôpital Tenon, Paris, France
    • ER9, Université Pierre et Marie Curie (Paris VI), Paris, France

Received 16 July 2009 ,Revised 4 August 2009 ,Accepted 13 November 2009.

References 

  1. Auger J, Eustache F. Standardisation de la classification morphologique des spermatozoïdes humains selon la méthode de David modifiée. Andrologie. 2000;10:358–373
  2. Brzek A. Alcohol and male fertility (preliminary report). Andrologia. 1987;19:32–36
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  15. Pajarinen J, Savolainen V, Perola M, et al. Glutathione S-transferase-M1 ‘null’ genotype and alcohol-induced disorders of human spermatogenesis. Int. J. Androl. 1996;19:155–163
  16. Pajarinen J, Savolainen V, Perola M, et al. Polymorphism in the cytochrome P450 2E1 gene and alcohol-induced disorders of human spermatogenesis. Int. J. Androl. 1996;19:314–322
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  19. World Health Organization, 1999. WHO Laboratory Manual for the Examination of Human Semen and Semen-Cervical Mucus Interaction 4th edition.
  20. World Health Organization, 2009. Alcohol: Facts and Figures. Available from: <http://www.who.int/substance_abuse/facts/alcohol/en/index.html> (accessed 20.10.09).

 Dr Nathalie Sermondade completed her studies in medicine at the Paris VI University in 2008. During her 4-year residency in medical biology, she specialized in reproductive biology, especially assisted reproductive technologies, and her MD was supervised by Dr. Jacqueline Mandelbaum in Tenon Hospital, Paris. She also obtained a Master’s degree in Science in Paris V University. She is currently undertaking a fellowship at Jean Verdier Hospital (Bondy, France) and is working on her PhD in Paris XIII University investigating the impact of nutrition on fertility.

PII: S1472-6483(09)00273-9

doi: 10.1016/j.rbmo.2009.12.003

Reproductive BioMedicine Online
Volume 20, Issue 3 , Pages 324-327 , March 2010

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