Prediction of in-vitro developmental competence of early cleavage-stage mouse embryos with compact time-lapse equipment

Pribenszky, Csaba; Losonczi, Eszter; Molnár, Miklós; Lang, Zsolt; Mátyás, Szabolcs; Rajczy, Klára; Molnár, Katalin; Kovács, Péter; Nagy, Péter; Conceicao, Jason; Vajta, Gábor

doi:10.1016/j.rbmo.2009.12.007

« Previous Next »Reproductive BioMedicine Online
Volume 20, Issue 3 , Pages 371-379, March 2010

Prediction of in-vitro developmental competence of early cleavage-stage mouse embryos with compact time-lapse equipment

Csaba Pribenszky
- Department of Animal Breeding and Genetics, Faculty of Veterinary Science, Szent István University, István u. 2, Budapest 1078, Hungary
- Corresponding author.
Eszter Losonczi
- ARTechnic Co. Research and Development, Csapó u. 13, Debrecen, Hungary
Miklós Molnár
- ARTechnic Co. Research and Development, Csapó u. 13, Debrecen, Hungary
Zsolt Lang
- Department of Biomathematics and Informatics, Faculty of Veterinary Science, Szent István University, István u. 2, Budapest 1078, Hungary
Szabolcs Mátyás
- Department of Embryology, KAÁLI Institute, Istenhegyi út 54/A, Budapest 1125, Hungary
Klára Rajczy
- Department of Embryology, KAÁLI Institute, Istenhegyi út 54/A, Budapest 1125, Hungary
Katalin Molnár
- Department of Embryology, KAÁLI Institute, Istenhegyi út 54/A, Budapest 1125, Hungary
Péter Kovács
- Department of Embryology, KAÁLI Institute, Istenhegyi út 54/A, Budapest 1125, Hungary
Péter Nagy
- Department of Electronics Technology, Faculty of Electrical Engineering and Informatics, Budapest University of Technology and Economics, Budapest, Hungary
Jason Conceicao
- PIVET Medical Centre, 166–168 Cambridge St., Perth, WA, Australia
Gábor Vajta
- Cairns Fertility Centre, 58–60 McLeod St., Cairns, Qld 4870, Australia

Received 6 July 2009; received in revised form 3 August 2009; accepted 26 November 2009. published online 21 January 2010.

Declaration: The authors Csaba Pribenszky, Miklos Molnar and Gabor Vajta are shareholders in the company Cryo-Innovation. The other authors declare no financial or commercial conflicts of interest.

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Csaba Pribenszky obtained a DVM degree (1998) and a PhD degree (2005) in the field of assisted reproductive technologies in Budapest, Hungary. Together with Mikos Molnar, he developed and patented the concept of ‘stress for stress tolerance’, utilizing sub-lethal hydrostatic pressure stress treatment to gametes, embryos, other cells and tissues in order to improve cell survival during subsequent procedures (e.g. cryopreservation, SCNT). His current focus is the application of the above method to human oocyte vitrification and the effect of different environmental factors on in-vitro embryo developmental dynamics and embryo fragmentation.