Reproductive BioMedicine Online
Volume 21, Issue 5 , Pages 631-635 , November 2010

IVF treatment should not be postponed for patients with high basal FSH concentrations

Received 20 October 2009 ,Revised 15 May 2010 ,Accepted 18 May 2010.

References 

  1. Abdalla H, Thum MY. Repeated testing of basal FSH levels has no predictive value for IVF outcome in women with elevated basal FSH. Hum. Reprod. 2006;21:171–174
  2. El-Toukhy T, Taranissi M. Which is more counterproductive: a brief delay or ‘start anyway’?. Hum. Reprod. 2006;21:2456–2457(author reply 2457–8)
  3. Lass A, Gerrard A, Abusheikha N, Akagbosu F, Brinsden P. IVF performance of women who have fluctuating early follicular FSH levels. J. Assist. Reprod. Genet. 2000;17:566–573
  4. Luna M, Grunfeld L, Mukherjee T, Sandler B, Copperman AB. Moderately elevated levels of basal follicle-stimulating hormone in young patients predict low ovarian response, but should not be used to disqualify patients from attempting in vitro fertilization. Fertil. Steril. 2007;87:782–787
  5. Roberts JE, Spandorfer S, Fasouliotis SJ, Kashyap S, Rosenwaks Z. Taking a basal follicle-stimulating hormone history is essential before initiating in vitro fertilization. Fertil. Steril. 2005;83:37–41
  6. Scott RT, Hofmann GE. Prognostic assessment of ovarian reserve. Fertil. Steril. 1995;63:1–11
  7. Scott RT, Toner JP, Muasher SJ, Oehninger S, Robinson S, Rosenwaks Z. Follicle-stimulating hormone levels on cycle day 3 are predictive of in vitro fertilization outcome. Fertil. Steril. 1989;51:651–654
  8. Scott RT, Hofmann GE, Oehninger S, Muasher SJ. Intercycle variability of day 3 follicle-stimulating hormone levels and its effect on stimulation quality in in vitro fertilization. Fertil. Steril. 1990;54:297–302
  9. Scott RT, Elkind-Hirsch KE, Styne-Gross A, Miller KA, Frattarelli JL. The predictive value for in vitro fertility delivery rates is greatly impacted by the method used to select the threshold between normal and elevated basal follicle-stimulating hormone. Fertil. Steril. 2008;89:868–878
  10. Sharif K, Elgendy M, Lashen H, Afnan M. Age and basal follicle stimulating hormone as predictors of in vitro fertilisation outcome. Br. J. Obstet. Gynaecol. 1998;105:107–112
  11. Watt AH, Legedza AT, Ginsburg ES, Barbieri RL, Clarke RN, Hornstein MD. The prognostic value of age and follicle-stimulating hormone levels in women over forty years of age undergoing in vitro fertilization. J. Assist. Reprod. Genet. 2000;17:264–268

 Dr Ettie Maman is a senior physician in the IVF unit, Department of Obstetric and Gynecology, Sheba Medical Center, Tel Aviv University, Israel. She graduated from Ben Gurion University, School of Medicine in Beer Sheba, Israel, in 1998. She completed her residency in Obstetrics and Gynecology at the Department of Obstetric and Gynecology, Sheba Medical Center. She worked as a research fellow at the Samuel Lunenfeld Research Institute, Mt Sinai Hospital, Toronto, Ontario, Canada. She joined the Sheba Medical Center IVF programme in 2006 and her research interests are related to infertility, in vitro maturation and stem cells.

PII: S1472-6483(10)00337-8

doi: 10.1016/j.rbmo.2010.05.013

Reproductive BioMedicine Online
Volume 21, Issue 5 , Pages 631-635 , November 2010

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