Abstract
Research question
Does placing an intrauterine balloon for different durations (7, 14 or 28 days) affect
the recurrence of intrauterine adhesions after hysteroscopic adhesiolysis?
Design
Prospective randomized control trial involving 138 patients recruited over a 12-month
period and followed up post-operatively for 15 months. The primary outcome measure
was the rate of adhesion reformation at third-look hysteroscopy.
Results
At third-look hysteroscopy, 8 weeks after the initial hysteroscopy, the adhesion recurrence
rate in women who had an intrauterine balloon for 28 days (20%) was significantly
(P < 0.01) lower than that of women who had the balloon for 14 days (55%) or 7 days
(36.8%).
Conclusions
Placing an intrauterine balloon for 28 days instead of 7 or 14 days after hysteroscopic
adhesiolysis resulted in a greater reduction in the recurrence rate of adhesions.
However, the study was underpowered to address whether the ongoing pregnancy rate
could be improved by keeping the balloon in the uterine cavity for a longer period
of time.
Graphical abstract
Graphical Abstract
Keywords
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Biography
Yuhuan Liu is a Professor of Obstetrics and Gynecology at the Capital Medical University, Beijing, China. She is Director of the Hysteroscopic Center and Gynecology at Fuxing Hospital, Beijing. Her current research focuses on uterine lesions and reproduction.
Article info
Publication history
Published online: December 10, 2019
Accepted:
November 30,
2019
Received in revised form:
November 13,
2019
Received:
July 19,
2019
Declaration: The authors report no financial or commercial conflicts of interest.Identification
Copyright
© 2019 Published by Elsevier Ltd on behalf of Reproductive Healthcare Ltd.
