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Male fertility as a marker for health

Published:October 05, 2021DOI:https://doi.org/10.1016/j.rbmo.2021.09.023

      Abstract

      Male reproduction is a complex biological process, and male factor infertility is increasingly recognized as a biomarker for overall male health. Emerging data suggest associations between male reproduction and medical disease (genetic, infectious, chronic comorbid conditions), psychological disease, environmental exposures, dietary habits, medications and substances of abuse, and even socioeconomic factors. There is also evidence that a diagnosis of male fertility is associated with future disease risk including cancer, metabolic disease and mortality. As such, there is a growing view that the male fertility evaluation is an opportunity to improve a man's health beyond his immediate reproductive goals, and also highlights the necessity of a multidisciplinary approach.

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      Biography

      Michael Eisenberg is an Associate Professor of Urology and the Director of Male Reproductive Medicine and Surgery at Stanford University School of Medicine, USA. He has authored numerous peer-reviewed articles and published in leading scientific journals and textbooks on the topic of associations between male fertility and health outcomes.
      Key Message
      Male factor infertility is a biomarker for overall health that is associated with present comorbid states and is predictive of future health including risk of cancer, metabolic disease and mortality. The male fertility evaluation is an opportunity to improve a man's overall health beyond his immediate reproductive goals.