- What are the effects of testosterone treatment on oocyte fertilization and preimplantation embryo development among transgender men who have undergone fertility preservation?
- Which early-diagnosed Klinefelter syndrome patients have been offered cryopreservation of testicular tissue as part of fertility preservation before spermatogonial stem cell (SSC) loss? Do these Klinefelter syndrome patients present with behavioural, cognitive and/or psychological problems? Does a testicular biopsy procedure have long-term effects on the gonadal development of Klinefelter syndrome patients?
- What are the real-life oncofertility practices in young women diagnosed with breast cancer?
- An age-related decline in fertility is a well-known physiologic effect related to decreases in oocyte quantity and quality (ACOG and ASRM, 2014). Older women who conceive naturally have an increased risk of fetal chromosomal abnormalities and pregnancy loss (Spandorfer and Chung, 2004). Despite this association, a global shift towards delayed childbearing has occurred (OECD Family Database, OECD, 2019). Age at first birth and the proportion of pregnancies in women over the age of 35 years have been increasing in the USA since 1980 (Martin et al., 2019).
- Do IVF treatments after conservative management of endometrial atypical hyperplasia or grade 1 endometrial adenocarcinoma (AH/EC) increase the risk of disease recurrence?
- How does follicle distribution evolve in the human ovarian cortex between the ages of 20 and 35 years?
- Does ovarian stimulation for oocyte vitrification affect disease-free survival and overall survival rates in women with early breast cancer?
- Is overnight transportation of ovarian tissue before cryopreservation in a centralized cryobank from the FertiPROTEKT network feasible?
- Female-to-male transgender people (trans men), are faced with the risk of losing their reproductive potential owing to gender affirming hormone treatment and genital reconstructive surgery. Transgender people also tend to start sex reassignment treatment at a young age, when reproductive wishes are not yet clearly defined nor fulfilled (De Sutter, 2001). About one-half of trans men, however, express the desire to have children (Wierckx et al., 2012). It is, therefore, recommended by the most recent Standards of Care of the World Professional Association for Transgender Health to clearly discuss fertility and fertility preservation before any treatment (Coleman et al., 2012).