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- Endometriosis is a relatively wide-spread benign but debilitating gynaecological disorder affecting women of reproductive age. Endometriosis develops following the implantation of endometrial tissue at ectopic locations, mainly peritoneal and on the surface of pelvic organs (Giudice, 2010). The prevalence of this disease varies from 4–50% in different populations (Cramer and Missmer, 2002; Eskenazi and Warner, 1997), and occurs in up to 50% of women with pelvic pain and/or infertility (Giudice, 2010; Meuleman et al., 2009).
- Male factor infertility is a growing problem worldwide. Considering that a male factor is involved in at least 20% of infertility cases, there is a need for better predictive markers of sperm function. The traditional sperm analysis based on sperm count and motility has been used for the diagnosis of male fertility for several decades, however, a significant number of men with normal sperm features remain unable to reach pregnancy. This fact clearly indicates the need to develop new male infertility tests to accurately diagnose the sperm samples from these individuals.