Free Access Articles
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- Letter
Accidentally delayed oocyte pickup – a challenge to the current paradigm
Reproductive BioMedicine OnlineVol. 31Issue 5p715–716Published online: August 4, 2015- Izhar Ben-Shlomo
- Johnny S. Younis
Cited in Scopus: 0Textbooks indicate that human ovulation occurs 38–39 hours after the administration of human chorionic gonadotrophin (HCG) in the setting of IVF. This known wisdom leads to the current practice of oocyte retrieval no later than 37 hours after HCG administration. The issue of the timing of HCG administration in relation to follicular size and hormonal response has received much attention (Chen et al., 2014), whereas only a few studies have been performed to examine the difference between the retrieval of oocytes earlier than 36 h following HCG administration, or later than 36 h but prior to 38 h (Garor et al., 2015; Raziel et al., 2006). - Review
Basic research in PCOS: are we reaching new frontiers?
Reproductive BioMedicine OnlineVol. 28Issue 6p669–683Published online: March 6, 2014- Izhar Ben-Shlomo
- Johnny S. Younis
Cited in Scopus: 21Polycystic ovarian syndrome (PCOS) is the leading cause for anovulatory infertility. It is diagnosed by two of the following three clinical criteria: oligomenorrhoea, hyperandrogenism and polycystic appearance of the ovaries. Weight loss and physical activity can lead to ovulation and conception. Lowering of serum insulin normalizes androgen concentrations whereas ovulation induction often causes ovarian hyperstimulation. Theca cells from PCOS ovaries may be more responsive to insulin than cells from non-PCOS ovaries.
